Introducing the SAGE REBREATHER™ by
An Amazingly Innovative PLATFORM TECHNOLOGY for Improving Health for MILLIONS
We are “Carboxic Breathers"—
INCREASING CO2 triggers breathing1,
while, DECREASING oxygen does NOT!
The SAGE Rebreather™ recycles exhaled CO2 for safe, efficient, and effective reuse in the body.
We are developing the SAGE Rebreather
- Raises body's CO2 level overcoming sleep apnea—clinically proven1
- Clinical studies used specialty gas cylinders to elevate CO21
- SAGE Rebreather safely retains specific amount of exhaled CO2...
- ...Increases CO2 concentration of next inhaled breath
- Four “dead space” channels overcome risk of overdosing
Next Step—Prove THIS DESIGN achieves targeted EtCO2* level in humans
√ Minimizing brain damage (TBI) and brain treatment represent a notably more time consuming and costly effort to validate in humans
√ The Q-Collar success [Qcollar.com] at FDA encourages confidence that we will be able to provide the data to FDA for its authorization
√ We have a broad and deep database of clinical studies for protection against brain damage
√ Preliminary data3 encourages further research of its application in the “golden hour” (30 mins) post-traumatic event to block Spreading Depolarizations (SDs) [known as precursor to CTEs]
√ Even more costly to validate will be the exciting experience (n=1) of researchers at University of Cincinnati, who unplugged a ventilator patient, provided an elevated CO2 treatment, and sent the patient home WALKING two weeks post-treatment
√ We seek funding for studies via grants with assistance from fund-raising consultants
√Other than TBI efforts, we anticipate remaining applications straightforward for clinicals and FDA
• Once the SAGE Rebreather was shown to function properly on the "bench," Dr. Smith focused on comfort for the SAGE user
• Sleep Apnea requires wearing a face cover overnight
• We focus on comfort because CPAP has only 20-25% compliance, i.e., up to 80% who try it stop using it due to a variety of complaints
• SAGE needs to be better, so we tried harder…
√Voila the FaceShield™
√An extra layer of fabric between skin & mask improves the “feel”
√Dr. Smith went the extra mile to…
Resulting in the following design...
*EndNotes/References
- A review of preventing central sleep apnea by inspired CO2
- Internal study conducted by Tracy Zundel, MD, Anesthesiologist & Director of the ICU at the Medical College of Wisconsin
- DeltaChase Proposal to DoD to Validate Ability of SAGE Rebreather to Block Spreading Depolarizations (SDs)